The Developments In COVID-19 Diagnosis, Treatment, And Control Strategies To End The Pandemic

Abstract

Rapid diagnostic tools, easily accessible repurposable medications, and timely containment measures to control the SARS-CoV-2 infection are crucial given the ongoing global spread of COVID-19. Recent developments in diagnostic testing include the use of artificial intelligence, IgG assay, spike protein detection, and CRISPR technology. Point-of-care rapid tests have also improved the gold standard reverse transcription polymerase chain (RT-PCR). In addition to antivirals, antiparasitics, anti-inflammatories, interferon, convalescent plasma, monoclonal antibodies, hyperimmunoglobulin, RNA interference, and mesenchymal stem cell therapy, supportive care, mechanical ventilation, and extracorporeal membrane oxygenation (ECMO) continue to be the preferred treatment options.
Clinical trials are underway for a variety of vaccines, including lentiviral, inactivated, viral, and RNA/DNA vaccines. Additionally, novel vaccine delivery systems that are portable and quickly deployable are also being developed. The possibility of a second wave of infection necessitates stringent and sensible control measures to keep fatalities to a minimum as nations have begun to relax the lockdown measures. Better containment tactics and references for additional research can be obtained from a better understanding of the developments in COVID-19 diagnostic tools, treatments, vaccines, and control measures.